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A dose-dependent mechanism is likely to be answerable for this effect, with lipophilicity as being the governing factor. In a given set, the presence of the cyclohexyl or an n-butyl team usually greater antifungal activity, with respect to both equally growth inhibition and cell de-pigmentation with the mycelium, suggesting that a higher lipophilicity may well make improvements to transportation inside the cells. SEM and TEM of M. grisea hyphae showed that treatment method with probably the most Energetic material (2h) prompted substantial ultrastructural results, specially over the endomembrane system, suggesting a mechanism of action much like that of most azole fungicides. Dissimilarities had been also observed, without alterations with the mobile wall obvious. In summary, several compounds confirmed greater inhibition than tricyclazole, and thus supply valuable new chemistry for control of M. grisea infections.

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Verlasst euch auf unsere sorgfältig kuratierte Auswahl, um euren Umzug stressfrei und reibungslos zu gestalten.

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